Therapeutics of pilocarpine

dc.contributor.authorCassell, Albert F.
dc.date.accessioned2017-09-20T22:01:44Z
dc.date.available2017-09-20T22:01:44Z
dc.date.issued1907
dc.date.published1907
dc.descriptionCitation: Cassell, Albert F. Therapeutics of pilocarpine. Senior thesis, Kansas State Agricultural College, 1907.
dc.descriptionMorse Department of Special Collections
dc.description.abstractIntroduction: HABITAT. Pilocarpine is an alkaloid of Pilocarpus, and to this primary action the crude drug owes its principal effect. The plant from which pilocarpine is derived grows in Brazil, South America. DESCRIPTION. It is about ten (10) to fifteen (15) C.M. long and from four (4) to six (6) C.M. broad. Short stalk, of a dull green color, coriaceous, pellucid- punctuate, mostly smooth; when bruised, slightly aromatic. Taste somewhat bitter and pungent.CONSTITUENTS. From this plant several other alkaloidal products are derived such as Jaborine C22H32N4O4; Pilocarpudine C10H14N2O2;Jaborandine whose composition is not exactly known. Pilocarpine is the hydrochlorate of an alkaloid obtained from pilocarpus with alcohol and hydrochloric acid by distillation and evaporation. The residue is dissolved in a slight excess of ammonia and chloroform, shaken with water, and then neutralized with hydrochloric acid. On evaporation crystals of hydrochlorate are formed. The properties of filocarpine,small white crystals having no odor but slightly bitter taste, are very soluble in water and alcohol, but almost insoluble in ether or chloroform. The drug can be used for a sialogogue cathartic or diaphoretic. Depending on the dose and for the end to which it is intended.
dc.identifier.urihttp://hdl.handle.net/2097/37922
dc.rightsThe organization that has made the Item available believes that the Item is in the Public Domain under the laws of the United States, but a determination was not made as to its copyright status under the copyright laws of other countries. The Item may not be in the Public Domain under the laws of other countries. Please refer to the organization that has made the Item available for more information.
dc.rights.urihttps://rightsstatements.org/vocab/NoC-US/1.0/
dc.subjectPilocarpine
dc.subjectPharmaceuticals
dc.subjectDrug Composition
dc.subject.AATTheses
dc.titleTherapeutics of pilocarpine
dc.typeText

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