Summation of blood glucose and TAG to characterise the 'metabolic load index'

dc.citation.doi10.1017/s0007114516003585
dc.citation.epage1563
dc.citation.issn0007-1145
dc.citation.issue9
dc.citation.jtitleBritish Journal of Nutrition
dc.citation.spage1553
dc.citation.volume116
dc.contributor.authorEmerson, Sam R.
dc.contributor.authorHaub, Mark D.
dc.contributor.authorTeeman, Colby S.
dc.contributor.authorKurti, Stephanie P.
dc.contributor.authorRosenkranz, Sara K.
dc.contributor.authoreidsararose
dc.contributor.authoreidhaub
dc.contributor.kstateRosenkranz, Sara K.
dc.contributor.kstateHaub, Mark D.
dc.date.accessioned2017-11-30T21:45:15Z
dc.date.available2017-11-30T21:45:15Z
dc.date.issued2016-10-24
dc.date.published2016
dc.descriptionCitation: Emerson, S. R., Haub, M. D., Teeman, C. S., Kurti, S. P., & Rosenkranz, S. K. (2016). Summation of blood glucose and TAG to characterise the 'metabolic load index'. British Journal of Nutrition, 116(9), 1553-1563. doi:10.1017/s0007114516003585
dc.description.abstractResearch points to postprandial glucose and TAG measures as preferable assessments of cardiovascular risk as compared with fasting values. Although elevated postprandial glycaemic and lipaemic responses are thought to substantially increase chronic disease risk, postprandial glycaemia and lipaemia have historically only been considered separately. However, carbohydrates and fats can generally 'compete' for clearance from the stomach, small intestine, bloodstream and within the peripheral cell. Further, there are previous data demonstrating that the addition of carbohydrate to a high-fat meal blunts the postprandial lipaemic response, and the addition of fat to a high-carbohydrate meal blunts the postprandial glycaemic response. Thus, postprandial glycaemia and lipaemia are interrelated. The purpose of this brief review is 2-fold: first, to review the current evidence implicating postprandial glycaemia and lipaemia in chronic disease risk, and, second, to examine the possible utility of a single postprandial glycaemic and lipaemic summative value, which will be referred to as the metabolic load index. The potential benefits of the metabolic load index extend to the clinician, patient and researcher.
dc.description.embargo2017-11
dc.description.versionArticle: Version of Record
dc.identifier.urihttp://hdl.handle.net/2097/38372
dc.relation.urihttps://doi.org/10.1017/s0007114516003585
dc.rightsThis Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
dc.rights.urihttp://journals.cambridge.org/images/fileUpload/documents/EJB_ctf.pdf
dc.subjectLipaemia
dc.subjectGlycaemia
dc.subjectCvd
dc.subjectMetabolism
dc.subjectCirculating Energy
dc.subjectCoronary-Heart-Disease
dc.titleSummation of blood glucose and TAG to characterise the 'metabolic load index'
dc.typeText

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