dc.contributor.author |
Fox, Jeffrie Thomas |
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dc.date.accessioned |
2008-08-08T20:34:53Z |
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dc.date.available |
2008-08-08T20:34:53Z |
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dc.date.issued |
2008-08-08T20:34:53Z |
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dc.identifier.uri |
http://hdl.handle.net/2097/908 |
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dc.description.abstract |
Two studies were undertaken to evaluate the use of Near Infrared Spectroscopy (NIRS) to determine arterial oxygen saturation (StO[subscript]2) in cattle with naturally-occurring Undifferentiated Bovine Respiratory Disease (UBRD) and experimentally-induced UBRD utilizing Mannheimia haemolytica.
The first study was a natural infection model utilizing 679 beef heifers weighing approximately 227 kg (500 pounds) originating from a southeastern U.S. salebarn. Heifers were evaluated for UBRD upon feedlot arrival, at revaccination, at day 35 on feed, at re-implant time, and two weeks prior to shipment for slaughter. Animals deemed to have UBRD were treated for UBRD and data was collected for 5 days following treatment, while a comparable healthy cohort was also evaluated at the time of treatment. There was a trend for NIRS to be able to predict the incidence of subsequent UBRD when cattle were evaluated on arrival (p=0.0552). However, the ability to detect UBRD in clinically ill cattle was not significantly different (p>0.1690) when compared to healthy cohorts in this model.
When carcass characteristics were evaluated at each time point, NIRS StO[subscript]2 values were able to differentiate between yield grades of animals with UBRD and healthy cohorts when evaluated at revaccination, day 35, re-implant, and pre-shipping (p<0.0199). NIRS tended to be able to differentiate yield grades at initial processing (p=0.0513). StO[subscript]2 was not a predictor of quality grade at any time point (p>0.1023), nor was there any correlation between lung lesions at slaughter and StO[subscript]2 (p>0.2292).
The second study involved 12 head of 181 kg (400 pound) heifers which were subjected to an experimental challenge model of Mannheimia haemolytica. Animals were evaluated daily and StO[subscript]2 readings recorded 12 hours pre-inoculation, at inoculation, 6, 12 and 24 hours post inoculation and daily for the next 12 days. While NIRS could not definitively differentiate healthy cohort cattle from challenge cattle (p>0.0713), there were trends toward challenge cattle having lower StO[subscript]2 values than healthy controls.
The authors conclude that while these studies did not provide conclusive evidence of the ability of NIRS to detect UBRD, further studies with a machine that is specifically calibrated and designed for use with cattle should be performed. |
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dc.description.sponsorship |
Pfizer Animal Health
235 East 42nd Street
Building 150 MS 40-09
New York City, NY 10017 |
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dc.language.iso |
en_US |
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dc.publisher |
Kansas State University |
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dc.subject |
Near Infrared Spectroscopy |
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dc.subject |
Bovine Respiratory Disease |
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dc.subject |
Cattle |
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dc.title |
Near infrared spectroscopy: a potential method to detect undifferentiated bovine respiratory disease |
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dc.type |
Thesis |
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dc.description.degree |
Master of Science |
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dc.description.level |
Masters |
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dc.description.department |
Department of Diagnostic Medicine/Pathobiology |
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dc.description.advisor |
Larry C. Hollis |
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dc.description.advisor |
Mark F. Spire |
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dc.subject.umi |
Agriculture, Animal Culture and Nutrition (0475) |
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dc.subject.umi |
Agriculture, Animal Pathology (0476) |
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dc.date.published |
2008 |
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dc.date.graduationmonth |
August |
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