Host Microbiota Influences Interactions Between Hosts And Pathogens

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dc.contributor.author Eppler, Megan E.
dc.contributor.author Grimes, Elizabeth A.
dc.contributor.author Hedden, Emily S.
dc.contributor.author Hodoameda, Peter
dc.contributor.author Hughes, Jamie M.
dc.contributor.author Isle, Kristin C.
dc.contributor.author Jojola-Mount, Valerie B.
dc.contributor.author Mason, Lindsay M.
dc.contributor.author Michel, Kristin
dc.contributor.author Viteri, Bianca Morejon
dc.contributor.author Ngwaga, Tshegofatso
dc.contributor.author Platt
dc.contributor.author Richie, Tanner G.
dc.contributor.author Stewart, Savannah C.
dc.contributor.author Wilson, Elizabeth J.
dc.date.accessioned 2021-01-12T23:08:16Z
dc.date.available 2021-01-12T23:08:16Z
dc.date.issued 2020-12
dc.identifier.uri https://hdl.handle.net/2097/41011
dc.description This manuscript is the product of the graduate class BIOL890B: Host-Pathogen Interactions, which was taught Fall 2020 at Kansas State University. All students in the class share authorship equally and are listed in alphabetical order by last name in alphabetical order. This course was co-taught by Dr. Kristin Michel (kmichel@ksu.edu) and Dr. Thomas Platt (tgplatt@ksu.edu), who serve as corresponding authors for this manuscript.
dc.description.abstract Bacterial microbiota have significant effects on host interactions with pathogens in both vertebrate and invertebrate organisms. Here we discuss the direct and indirect impacts of microbiota on defense against pathogens. We found that microbiota have direct effects on host defense against pathogens through interference and niche competition, and by influencing host immune system development and function. The host microbiota also impacts host-pathogen interactions beyond immunity, by influencing physical barriers and physiological responses. In addition, it can influence the establishment of tumorigenic microbes thereby increasing cancer risk. Thus, the relationship between the host and its microbiota has short- and long-term impacts on overall health. Research that aims to identify and characterize the mechanisms that underlie these direct and indirect effects on host health will inform future medical treatments. en_US
dc.language.iso en_US en_US
dc.rights This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
dc.rights.uri https://rightsstatements.org/vocab/InC/1.0/
dc.title Host Microbiota Influences Interactions Between Hosts And Pathogens en_US
dc.type Text en_US
dc.date.published 2020 en_US


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This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). Except where otherwise noted, the use of this item is bound by the following: This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

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