One Drop: Lab on a Chip

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dc.contributor.author Richards, Megan
dc.contributor.author Brungardt, Kaley
dc.contributor.author Schuette, Kendra
dc.date.accessioned 2017-08-30T22:18:34Z
dc.date.available 2017-08-30T22:18:34Z
dc.date.issued 2017
dc.identifier.uri http://hdl.handle.net/2097/36383
dc.description Citation: Richards, M., Brungardt, K., & Schuette, K. (2017). One Drop: Lab on a Chip. Unpublished manuscript, Kansas State University, Manhattan, KS.
dc.description Kirmser Undergraduate Research Award - Group, honorable mention
dc.description.abstract Lab on a chip devices are currently being studied to aid in blood based diagnostic assaytests for personalized medicine applications. These biosensors are appealingdue to their low cost, simplicity of use, and quick feedback of results. Thegoal of team One Drop was to design a chip that simplifies the diagnosis ofbreast and ovarian cancer by searching for certain antigens in thebloodstream. The main objective for this semester has been to design amicrofluidic lab on a chip device that will mix blood and reagentstreams to generate turbulent flows within a fluidic chamber using noexternal forces. The resulting fluid mixture will settle within the device for further analysis. One Drop was able to prototype four differentmicrofluidic flow designs in SolidWorks for further simulation testing inCOMSOL multiphysics modeling with the aid of a theoretical analysis foranalyzing fluid flow properties. One design was selected due to its highdiffusive capability for efficient mixing of blood and reagent streams. Eachdesign was compared through qualitative analysis, a simple COMSOL simulation,and 3D printing capabilities.
dc.publisher Kansas State University. K-State Libraries
dc.rights This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
dc.rights.uri http://rightsstatements.org/vocab/InC/1.0/
dc.subject Lab on a chip
dc.subject Biosensors
dc.subject Blood-based diagnostic assay tests
dc.subject Personalized medicine
dc.subject Microfluidic device
dc.subject Cancer diagnosis
dc.title One Drop: Lab on a Chip
dc.type Text
dc.description.advisor Edwin Brokesh
dc.date.published 2017
dc.contributor.authoreid kaley1
dc.contributor.authoreid megr13
dc.contributor.authoreid kkschuette
dc.description.course Biological Systems Engineering Senior Design: BAE536 and BAE636


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This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). Except where otherwise noted, the use of this item is bound by the following: This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

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