Lycopenoids: Are lycopene metabolites bioactive?

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dc.contributor.author Lindshield, Brian L.
dc.contributor.author Canene-Adams, Kirstie
dc.contributor.author Erdman, John W. Jr.
dc.date.accessioned 2008-11-20T14:25:33Z
dc.date.available 2008-11-20T14:25:33Z
dc.date.issued 2008-11-20T14:25:33Z
dc.identifier.uri http://hdl.handle.net/2097/1009
dc.description.abstract In vitro lycopene is the most potent antioxidant among carotenoids. While antioxidant function may be relevant to health, we hypothesize that metabolites of lycopene may be bioactive and responsible for the beneficial effects of tomato product consumption. We term these metabolites "lycopenoids," which we believe may be produced from carotenoid monooxygenase (CMO) II, paralleling the production of retinoids from [beta]-carotene by CMO I. We present evidence suggesting that tomato carotenoid metabolites may be responsible for the reduced risk of prostate cancer seen in men consuming high levels of tomato products. Finally, we identify gaps in knowledge in this evolving area of carotenoid research. en
dc.relation.uri http://www.elsevier.com/wps/find/journaldescription.cws_home/622787/description#description en
dc.subject Lycopenoids en
dc.subject Lycopene en
dc.subject Prostate cancer en
dc.subject Carotenoids en
dc.subject Tomato en
dc.subject Carotenoid monooxygenase en
dc.subject CMO en
dc.subject Beta-carotene
dc.subject Phytoene
dc.subject Phytofluene
dc.title Lycopenoids: Are lycopene metabolites bioactive? en
dc.type Article (author version) en
dc.date.published 2007 en
dc.citation.epage 140 en
dc.citation.jtitle Archives of biochemistry and biophysics en
dc.citation.spage 136 en
dc.citation.volume 458 en
dc.contributor.authoreid blindsh en


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