Qiu, Chen2014-07-222014-07-222014-08-01http://hdl.handle.net/2097/18129In the classic split-plot design where whole plots have a completely randomized design, the conventional analysis approach assumes a compound symmetry (CS) covariance structure for the errors of observation. However, often this assumption may not be true. In this report, we examine using different covariance models in PROC MIXED in the SAS system, which are widely used in the repeated measures analysis, to model the covariance structure in the split-plot data in which the simple compound symmetry assumption does not hold. The comparison of the covariance structure models in PROC MIXED and the conventional split-plot model is illustrated through a simulation study. In the example analyzed, the heterogeneous compound symmetry (CSH) covariance model has the smallest values for the Akaike and Schwarz’s Bayesian information criteria fit statistics and is therefore the best model to fit our example data.en-USSplit-plotCovariance StructureRepeated MeasuresMixed ModelReportStatistics (0463)