Steidinger, M.U.Dau, D.Tokach, Michael D.DeRouchey, Joel M.Goodband, Robert D.Nelssen, Jim L.Dritz, Steven S.2009-11-102009-11-102009-11-10http://hdl.handle.net/2097/2124A total of 1,008 weanling pigs (12.0 lb and 19 d of age) were used in a 42-d experiment to compare different antibiotic regimens on growth performance and economic return. From d 0 to 11 and d 11 to 21, pigs were fed diets containing no antibiotic, a combination of Denagard (Novartis Animal Health, Greensboro, NC) at 35 g/ton and chlortetracycline at 400 g/ton (Denagard/CTC), or Pulmotil (Elanco, Greenfield, IN; 363 g/ton from d 0 to 11 and 181 g/ton from d 11 to 21). From d 21 to 42, pigs previously fed Denagard/CTC or Pulmotil were fed diets containing no medication, Denagard/CTC, or a combination of Mecadox (Philbro Animal Health Corp., Ridgefield Park, NJ) at 25 g/ton and oxytetracycline at 400 g per ton (Mecadox/OTC). Adding Denagard/CTC or Pulmotil to the diet from d 0 to 11 and d 11 to 21 improved (P < 0.01)ADG, ADFI, F/G, and income over feed cost (IOFC). There were no differences (P > 0.21) in ADG or ADFI between pigs fed Denagard/CTC and pigs fed Pulmotil; however, pigs fed Denagard/CTC tended to have better (P < 0.09) F/G from d 0 to 21. Feed cost was also lower (P < 0.01) and IOFC was greater (P < 0.03) from d 0 to 21 for pigs fed Denagard/CTC than for pigs fed Pulmotil. Adding Denagard/CTC or Mecadox/OTC to the diet from d 21 to 42 increased (P < 0.05) ADG, ADFI, and IOFC compared with feeding no antibiotic, but there were no differences (P > 0.17) in pig performance or IOFC between pigs fed Denagard/CTC and Mecadox/OTC. For the overall trial, adding antibiotics to the diet during any phase improved (P < 0.05) ADG, ADFI, F/G, and IOFC. These results demonstrate that adding antibiotics to the nursery diet improved pig performance and economical return on this commercial farm.AntimicrobialSwineComparison of different antimicrobial sequences on nursery pig performance and economic returnConference paper