Kastner, JustinPowell, Douglas A.Crowley, TerryHuff, Karen2008-03-282008-03-282008-03-28http://hdl.handle.net/2097/583A century before bovine spongiform encephalopathy, Great Britain and North America grappled with an equally maddening disease in cattle: pleuro-pneumonia. The subject of a decades-long trade dispute in the nineteenth-century transatlantic region, pleuro-pneumonia attracted the attention of livestock farmers, diplomats, shipping moguls, veterinarians, public health regulators, and journalists. Scientific controversy aggravated the dispute; veterinary officials elaborated scientific opinions and regulatory orders amidst a prevailing confusion about microbiology and disease diagnostics. In this context emerged William Williams, an Edinburgh-based professor whose convictions spawned repeated disagreements with the British government’s diagnoses of pleuro-pneumonia in cattle from the United States and Canada.International agricultural tradeFood safety and securityHistory of scienceTransatlantic tradeWilliam WilliamsPleuro-pneumoniaArticle (author version)