Flohr, Joshua R.Woodworth, Jason C.Bergstrom, J. R.Tokach, Michael D.Dritz, Steven S.Goodband, Robert D.DeRouchey, Joel M.2017-11-302017-11-30http://hdl.handle.net/2097/38308Citation: Flohr, J. R., Woodworth, J. C., Bergstrom, J. R., Tokach, M. D., Dritz, S. S., Goodband, R. D., & DeRouchey, J. M. (2016). Evaluating the impact of maternal vitamin D supplementation: I. Sow performance, serum vitamin metabolites, and neonatal muscle characteristics. Journal of Animal Science, 94(11), 4629-4642. doi:10.2527/jas2016-0409In Exp. 1, 56 gestating sows (PIC 1050; 35 d postinsemination) were used in a 30-d trial to determine serum 25(OH)D-3 response to increasing concentrations of dietary vitamin D3. Sows were randomly allotted to 1 of 7 dietary D3 treatments (200, 800, 1,600, 3,200, 6,400, 12,800, or 25,600 IU of added D3 per kilogram of complete diet) with 8 sows per treatment. Increasing D-3 increased (quadratic; P < 0.001) serum 25(OH)D-3 with the response depicted by the prediction equation: serum 25(OH) D3, ng/mL = 35.1746 + (0.002353 x dietary D-3, IU/d)- (0.0000000156 x dietary D3, IU/d(2)). In Exp. 2, 112 sows and their litters were used to determine the effects of dietary vitamin D regimen on sow performance, subsequent preweaning pig performance, neonatal bone and muscle characteristics, and serum vitamin metabolites. Sows were allotted to 1 of 4 dietary treatments 3 to 5 d following breeding: 800, 2,000, or 9,600 IU of D-3 per kilogram of the diet or 50 mu g of 25(OH) D-3 (2,000 IU of D-3 equivalent from Hy- D, DSM Nutritional Products, Parsippany, NJ) per kilogram of diet. There were 25 to 27 sows per treatment. Increasing dietary D-3 increased (linear, P = 0.001) serum 25(OH) D-3 of sows on d 100 of gestation, at farrowing, and at weaning. Increasing D-3 in sow diets increased piglet serum 25(OH)D-3 at birth (linear, P = 0.001) and weaning (quadratic, P = 0.033). Sows fed 50 mu g of 25(OH)D-3/kg had intermediate (P < 0.004) serum 25(OH)D-3 concentrations on d 100 of gestation, at farrowing, and at weaning compared with sows fed 2,000 IU of D-3/kg and sows fed 9,600 IU of D3/kg. Pigs from sows fed 50 mu g of 25(OH) D3/ kg had greater serum 25(OH)D-3 compared with pigs from sows fed 2,000 IU of D-3/kg, but at weaning, serum 25(OH)D-3 concentrations were similar. Also, pigs from sows fed 9,600 IU of D-3/kg had greater (P = 0.011) serum 25(OH) D3 at birth and weaning compared with pigs from sows fed 50 mu g of 25(OH) D-3/kg. Maternal performance, litter characteristics, neonatal bone ash content, and neonatal muscle fiber characteristics were largely unaffected by the dietary vitamin D treatments. Overall, D3 and 25(OH) D3 are both useful at increasing serum 25(OH)D-3 concentrations, but more D3 (on an equivalent IU basis) is needed to achieve similar serum 25(OH)D-3 responses compared with feeding 25(OH)D-3. Concentration of maternal vitamin D supplementation in lactation impacted milk transfer of the vitamin more so than the form of the vitamin, as evidence by the weaned pig serum 25(OH)D-3 concentrations.Copyright © 2016. American Society of Animal Science. This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).25(Oh)D-3Sow NutritionVitamin DMuscle CharacteristicsSkeletal-MuscleReproductive-PerformanceArticle