Complete genome sequence of an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus

Wu, JiajunChen, NanhuaHan, WeiCao, ZhenDeng, XiaoyuWang, LilinYu, XiulingZhou, ZhiLi, XiangdongShi, Jishu N.Tian, Kegong2012-06-262012-06-262012-03-22http://hdl.handle.net/2097/13957JXA1-P170 is an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) that has been passaged in vitro 170 times. Vaccination with JXA1-P170 cannot protect pigs against JXA1 challenge. Compared with the parental virus JXA1, JXA1-P170 contains 1 nucleotide (nt) deletion and 113 nt mutations leading to 59 amino acid substitutions. Here we announce the first complete genome sequence of the overattenuated HP-PRRSV.Free content from ASM.Complete genome sequenceJXA1-P170Highly pathogenic porcine reproductive and respiratory syndrome virusComplete genome sequence of an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virusArticle (publisher version)