Evaluation of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA
| dc.citation.doi | 10.1186/s13071-015-0897-z | |
| dc.citation.issn | 1756-3305 | |
| dc.citation.issue | 1 | |
| dc.citation.jtitle | Parasites & Vectors | |
| dc.citation.spage | 7 | |
| dc.citation.volume | 8 | |
| dc.contributor.author | Dryden, Michael W. | |
| dc.contributor.author | Smith, Victorene E. | |
| dc.contributor.author | Chwala, M. | |
| dc.contributor.author | Jones, E. | |
| dc.contributor.author | Crevoiserat, L. | |
| dc.contributor.author | McGrady, J. C. | |
| dc.contributor.author | Foley, K. M. | |
| dc.contributor.author | Patton, P. R. | |
| dc.contributor.author | Hawkins, A. | |
| dc.contributor.author | Carithers, D. | |
| dc.contributor.authoreid | dryden | |
| dc.date.accessioned | 2016-04-04T22:44:50Z | |
| dc.date.available | 2016-04-04T22:44:50Z | |
| dc.date.issued | 2015-05-24 | |
| dc.date.published | 2015 | |
| dc.description | Citation: Dryden, M. W., Smith, V., Chwala, M., Jones, E., Crevoiserat, L., McGrady, J. C., . . . Carithers, D. (2015). Evaluation of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA. Parasites & Vectors, 8, 7. doi:10.1186/s13071-015-0897-z | |
| dc.description | Background: A study was conducted to evaluate the effectiveness of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA. Evaluations of on-animal and premises flea burdens, flea sex structure and fed-unfed premises flea populations were conducted to more accurately assess flea population dynamics in households. Methods: Thirty seven naturally flea infested dogs in 23 homes in Tampa, FL were enrolled in the study and treated with afoxolaner chewables. Chewables (NexGard (R) Chewables; Merial) were administered according to label directions by study investigators on study day 0 and once again between study days 28 and 30. Flea infestations on pets were assessed using visual area thumb counts and premises flea infestations were assessed using intermittent-light flea traps on days 0, 7, 14, 21, and once between study days 28-30, 40-45, and 54-60. Results: Within 7 days of administration of afoxolaner chewable tablets, flea counts on dogs were reduced by 99.3 %. By one month post-treatment, total flea counts on dogs were reduced by 99.9 %, with 97.3 % (36/37) of the dogs being flea free. Following the second dosing on study day 28-30, total on-dog flea burden was reduced by 100 % on days 40-45 and 54-60. On day 0, the traps collected a geometric mean of 18.2 fleas. Subsequent reductions in emerging flea populations were 97.7 and 100 % by days 28-30 and 54-60, respectively. There were 515 total fleas (Ctenocephalides felis felis) collected in the intermittent light flea traps on day 0, and 40.4 % of those fleas displayed visual evidence of having fed. Seven days after initial treatment, only 13.1 % of the fleas contained blood and by day 14 only 4.9 % of the fleas collected in traps displayed evidence of having fed. On day 0, prior to treatment, 60 % of the unfed fleas collected in intermittent-light flea traps were females, but by days 28-30, unfed males accounted for 78 % of the population. Conclusions: This in-home investigation conducted during the summer of 2014 in subtropical Tampa, FL demonstrated that afoxolaner chewables rapidly and effectively eliminated flea populations in infested dogs and homes. | |
| dc.identifier.uri | http://hdl.handle.net/2097/32274 | |
| dc.relation.uri | https://doi.org/10.1186/s13071-015-0897-z | |
| dc.rights | Attribution 4.0 International (CC BY 4.0) | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Ctenocephalides Felis Felis | |
| dc.subject | Cat Flea | |
| dc.subject | Dogs | |
| dc.subject | Field Study | |
| dc.subject | Tampa Fl | |
| dc.subject | Afoxolaner | |
| dc.title | Evaluation of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA | |
| dc.type | Article |
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