A method to measure nanomechanical properties of biological objects

Ploscariu, Nicoleta; Szoszkiewicz, Robert

dc.citation.doi	10.1063/1.4858411	en_US
dc.citation.jtitle	Applied Physics Letters	en_US
dc.citation.spage	263702	en_US
dc.citation.volume	103	en_US
dc.contributor.author	Ploscariu, Nicoleta
dc.contributor.author	Szoszkiewicz, Robert
dc.contributor.authoreid	szosz	en_US
dc.date.accessioned	2014-03-05T22:33:47Z
dc.date.available	2014-03-05T22:33:47Z
dc.date.issued	2014-03-05
dc.date.published	2013	en_US
dc.description.abstract	We postulate that one will be able to quantitatively infer changes in the mechanical properties of proteins, cells, and other biological objects (BO) by measuring the shifts of several thermally excited resonance frequencies of atomic force microscopy cantilevers in contact with BOs. Here, we provide a method to extract spring constants and molecular damping factors of BOs in biologically relevant phosphate buffered saline medium and using compliant AFM cantilevers with a small aspect ratio (a ratio of length to width).	en_US
dc.identifier.uri	http://hdl.handle.net/2097/17206
dc.language.iso	en_US	en_US
dc.relation.uri	https://doi.org/10.1063/1.4858411	en_US
dc.rights	This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).	en_US
dc.rights.uri	http://rightsstatements.org/vocab/InC/1.0/
dc.subject	Biological objects	en_US
dc.subject	Measurement	en_US
dc.subject	Atomic force microscopy	en_US
dc.subject	Spring constants	en_US
dc.subject	Molecular damping factors	en_US
dc.title	A method to measure nanomechanical properties of biological objects	en_US
dc.type	Article (publisher version)	en_US

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