A method to measure nanomechanical properties of biological objects
| dc.citation.doi | 10.1063/1.4858411 | en_US |
| dc.citation.jtitle | Applied Physics Letters | en_US |
| dc.citation.spage | 263702 | en_US |
| dc.citation.volume | 103 | en_US |
| dc.contributor.author | Ploscariu, Nicoleta | |
| dc.contributor.author | Szoszkiewicz, Robert | |
| dc.contributor.authoreid | szosz | en_US |
| dc.date.accessioned | 2014-03-05T22:33:47Z | |
| dc.date.available | 2014-03-05T22:33:47Z | |
| dc.date.issued | 2014-03-05 | |
| dc.date.published | 2013 | en_US |
| dc.description.abstract | We postulate that one will be able to quantitatively infer changes in the mechanical properties of proteins, cells, and other biological objects (BO) by measuring the shifts of several thermally excited resonance frequencies of atomic force microscopy cantilevers in contact with BOs. Here, we provide a method to extract spring constants and molecular damping factors of BOs in biologically relevant phosphate buffered saline medium and using compliant AFM cantilevers with a small aspect ratio (a ratio of length to width). | en_US |
| dc.identifier.uri | http://hdl.handle.net/2097/17206 | |
| dc.language.iso | en_US | en_US |
| dc.relation.uri | https://doi.org/10.1063/1.4858411 | en_US |
| dc.rights | This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). | en_US |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | |
| dc.subject | Biological objects | en_US |
| dc.subject | Measurement | en_US |
| dc.subject | Atomic force microscopy | en_US |
| dc.subject | Spring constants | en_US |
| dc.subject | Molecular damping factors | en_US |
| dc.title | A method to measure nanomechanical properties of biological objects | en_US |
| dc.type | Article (publisher version) | en_US |
