Feline mast cell tumors, a review

dc.contributor.authorLuu, Savannah Wong
dc.date.accessioned2019-04-17T18:11:57Z
dc.date.available2019-04-17T18:11:57Z
dc.date.graduationmonthMay
dc.date.issued2019-05-01
dc.description.abstractMast cell tumors (MCTs) account for up to 15% of all tumors in cats, and have been reported as the third most frequent tumor in cats after lymphoid and mammary neoplasms. Feline MCTs can be divided into three forms based on anatomic location: cutaneous, splenic, and intestinal. Although cutaneous MCTs were once thought to be invariably benign, some are capable of disseminating and metastasizing; therefore, it is important to distinguish these tumors, in order for appropriate treatment to occur / be implemented. Splenic and intestinal MCT seem to have worse prognoses, although there is less literature documenting these forms of feline MCT. Several chemotherapeutics have been investigated in the setting of canine MCT, and recently, toceranib (Palladia) has been approved by the FDA as a targeted chemotherapeutic agent for management of canine MCT. However, studies on the effectiveness of conventional chemotherapeutic agents for the treatment of feline MCT are rare let alone studies on specific therapies to manage this disease in cats. This review summarizes the current diagnostic avenues to detect and characterize mast cell disease in felines and the available treatment options and shows the need for further research into this important disease in cats.
dc.description.advisorRaelene Wouda
dc.description.degreeMaster of Science in Biomedical Sciences
dc.description.departmentDepartment of Clinical Sciences
dc.description.levelMasters
dc.identifier.urihttp://hdl.handle.net/2097/39564
dc.language.isoen_US
dc.publisherKansas State University
dc.rights© the author. This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectMast cell
dc.subjectFeline
dc.subjectMast cell tumor
dc.subjectChemotherapy
dc.subjectCat
dc.titleFeline mast cell tumors, a review
dc.typeReport

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