Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses

dc.citation.doi10.1371/journal.ppat.1004819
dc.citation.issn1553-7366
dc.citation.issue6
dc.citation.jtitlePLoS Pathogens
dc.citation.spage6
dc.citation.volume11
dc.contributor.authorMa, Wenjun
dc.contributor.authorGarcia-Sastre, A.
dc.contributor.authorSchwemmle, M.
dc.contributor.authoreidwjma
dc.date.accessioned2016-04-04T22:45:00Z
dc.date.available2016-04-04T22:45:00Z
dc.date.issued2015-06-04
dc.date.published2015
dc.descriptionCitation: Ma, W. J., Garcia-Sastre, A., & Schwemmle, M. (2015). Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses. Plos Pathogens, 11(6), 6. doi:10.1371/journal.ppat.1004819
dc.descriptionInfluenza A viruses (IAVs) are important zoonotic pathogens that cause epidemic outbreaks in poultry, wild birds, swine, and other mammals. In humans, IAVs cause severe respiratory illness, and zoonotic transmission of IAVs from avian reservoirs poses a constant threat to the public health, as exemplified by the recent outbreak of an avian IAV of the H7N9 subtype [1]. Aquatic birds are considered to be the major reservoir of IAVs, and 16 hemagglutinin (HA) and nine neuraminidase (NA) viral subtypes have been isolated from avian species to date. It is now well documented that from time to time IAVs overcome the species barrier and establish new lineages in other animals, including domestic animals, sea mammals, and humans (Fig 1). Our understanding of IAVs was recently challenged by the identification of two novel genome sequences of influenza A-like viruses from bat specimens by next-generation sequencing. These viruses were provisionally designated "H17N10" (from yellow-shouldered fruit bats [Sturnira lilium] in Guatemala) and "H18N11" (from flat-faced fruit bats [Artibeus planirostris] in Peru) [2,3], which might signal an expansion of IAV host range (Fig 1).
dc.identifier.urihttp://hdl.handle.net/2097/32284
dc.relation.urihttps://doi.org/10.1371/journal.ppat.1004819
dc.rightsAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectPolymerase
dc.subjectSite
dc.subjectMicrobiology
dc.subjectParasitology
dc.subjectVirology
dc.titleExpected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses
dc.typeArticle

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