Complete genome sequence of an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus
Date
2012-03-22
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Abstract
JXA1-P170 is an overattenuated highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) that has been passaged in vitro 170 times. Vaccination with JXA1-P170 cannot protect pigs against JXA1 challenge. Compared with the parental virus JXA1, JXA1-P170 contains 1 nucleotide (nt) deletion and 113 nt mutations leading to 59 amino acid substitutions. Here we announce the first complete genome sequence of the overattenuated HP-PRRSV.
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Keywords
Complete genome sequence, JXA1-P170, Highly pathogenic porcine reproductive and respiratory syndrome virus
