Fate of fumonisins in cattle fed contaminated feed

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dc.contributor.author Thakur, R.A.
dc.contributor.author Wallace, N.
dc.contributor.author Smith, J. Scott
dc.contributor.author Nagaraja, Tiruvoor G.
dc.date.accessioned 2010-09-03T20:59:13Z
dc.date.available 2010-09-03T20:59:13Z
dc.date.issued 2010-09-03T20:59:13Z
dc.identifier.uri http://hdl.handle.net/2097/4840
dc.description.abstract Fumonisins are water-soluble carcinogenic mycotoxins produced by many species of Fusarium molds. Fumonisins occur widely in corn, making them a problem in corn-based feed. Their toxicity has been established in many species. However, their effects on cattle and the potential of carryover to the human diet through beef has not been studied extensively. A 30-day cattle feeding study was conducted by feeding fumonisin-contaminated corn grits dosed at 400 g/g fumonisin B1 (FB1) and 130 g/g fumonisin B2 (FB2) to 3 steers averaging 480 lb. Premortem analysis involved urinalysis; tests for liver functionality; and analysis of the blood, urine, and feces for the presence of fumonisins or their metabolites. Postmortem analysis involved necropsy, analysis of tissue for fumonisins, and histopathology. The test animals showed some s light liver abnormalities. The feces contained unmetabolized FB1 and FB2 ($80% of the fed dose), and trace amounts were detected in the urine. Tissue analysis resulted in detection of 2.1 g/g FB 1 in the liver, 0.1 g/g FB1 in the muscle, and 0.02 g/g FB1 in the kidney, indicating a high feed:tissue ratio, and consequently insignificant carryover into the human diet. en_US
dc.publisher Kansas State University. Agricultural Experiment Station and Cooperative Extension Service en_US
dc.relation.isPartOf Cattlemen’s Day, 1996 en_US
dc.relation.isPartOf Kansas Agricultural Experiment Station contribution; no. 96-334-S en_US
dc.relation.isPartOf Report of progress (Kansas State University. Agricultural Experiment Station and Cooperative Extension Service); 756 en_US
dc.subject Beef en_US
dc.subject Fumonisins en_US
dc.subject Toxicity en_US
dc.subject Residues in tissues en_US
dc.title Fate of fumonisins in cattle fed contaminated feed en_US
dc.type Conference paper en_US
dc.date.published 1996 en_US
dc.citation.epage 16 en_US
dc.citation.spage 14 en_US
dc.description.conference Cattlemen's Day, 1996, Kansas State University, Manhattan, KS, March 1, 1996 en_US
dc.contributor.authoreid jsschem en_US
dc.contributor.authoreid tnagaraj en_US


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