Comparison of bovine transfer factor and Micotil®: effects on health and performance of receiving heifers

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dc.contributor.author Montgomery, Sean P.
dc.contributor.author Greenquist, M.A.
dc.contributor.author Sindt, J.J.
dc.contributor.author Miller, W.F.
dc.contributor.author Pike, J.N.
dc.contributor.author Good, E.J.
dc.contributor.author Loe, E.R.
dc.contributor.author Sulpizio, M.J.
dc.contributor.author Kessen, T.J.
dc.contributor.author Drouillard, James S.
dc.date.accessioned 2010-08-03T17:51:53Z
dc.date.available 2010-08-03T17:51:53Z
dc.date.issued 2010-08-03T17:51:53Z
dc.identifier.uri http://hdl.handle.net/2097/4404
dc.description.abstract Transfer factors are antigen-specific products of T lymphocytes that are capable of transferring delayed-type hypersensitivity and cell-mediated immunity. We evaluated bovine transfer factor (TF) for use in receiving cattle. Crossbred beef heifers (n = 665) initially weighing 495 lb were used to determine the effects of TF on the health and performance of beef cattle during a 36-day receiving period. Heifers were processed within 24 hours after arrival. Treatments were subcutaneous injection with 1.5 ml of Micotil®/100 lb of body weight or oral administration of 700 mg of TF isolated from bovine colostrum. Heifers given TF during initial processing received an additional 700 mg/day of TF in the diet on days 2 through 5. The percentage of heifers treated at least one, two, or three times for bovine respiratory disease (BRD) was greater (P<0.01) for heifers given TF than for heifers given Micotil (72.5 vs. 47.1; 31.5 vs. 14.7; and 18.0 vs. 4.2, respectively). There were no differences between TF and Micotil with respect to dry matter intake, weight gain, or gain efficiency of heifers. Subsequent in vitro fermentations indicated that TF protein is readily degraded by ruminal microbes. Oral administration of TF was not as effective as Micotil injection in decreasing BRD in receiving cattle. en_US
dc.publisher Kansas State University. Agricultural Experiment Station and Cooperative Extension Service en_US
dc.relation.isPartOf Cattlemen's Day, 2004 en_US
dc.relation.isPartOf Kansas Agricultural Experiment Station contribution; no. 04-242-S en_US
dc.relation.isPartOf Report of progress (Kansas State University. Agricultural Experiment Station and Cooperative Extension Service); 923 en_US
dc.subject Beef en_US
dc.subject Micotil® en_US
dc.subject Bovine transfer factor en_US
dc.title Comparison of bovine transfer factor and Micotil®: effects on health and performance of receiving heifers en_US
dc.type Conference paper en_US
dc.date.published 2004 en_US
dc.citation.epage 58 en_US
dc.citation.spage 55 en_US
dc.description.conference Cattlemen's Day, 2004, Kansas State University, Manhattan, KS, March 5, 2004 en_US
dc.contributor.authoreid jdrouill en_US


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