Neuronal in vitro impact of Amblyommaamericanumsalivary glands extracts

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dc.contributor.author Leierer, Madi
dc.contributor.author Montenegro-Cadena, Lidia
dc.contributor.author Maldonado, Paulina
dc.contributor.author Londono-Renteria, Berlin
dc.date.accessioned 2019-09-06T16:24:51Z
dc.date.available 2019-09-06T16:24:51Z
dc.date.issued 2018-12-14
dc.identifier.uri http://hdl.handle.net/2097/40142
dc.description.abstract When a tick feeds off a host, the salivary glands of the tick excrete saliva to assist the tick in feeding (1). The reason saliva assists the tick in consuming its blood meal is due to its immunosuppressive, anti-inflammatory, and anti-coagulant properties (2).Tick salivary glands also play an important role in the transmission of tick-borne pathogens (3). We wanted to investigate the effect of tick salivary gland extracts (SGE) on human neurons. For our experiment, the organism whose salivary gland extract we used was the Amblyomma americanum. We compared the effects of salivary gland extract from ticks collected in the field and ticks reared in a lab colony. Our results showed that the salivary gland extract from the two types of ticks affected the neurons differently, and the salivary gland extract of the field tick was more damaging to the neurons. This indicates that SGE from field ticks, together with infectious agents, could result in a more severe neuronal impairment in a human host than the infectious agent alone.
dc.language.iso en_US
dc.rights This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
dc.rights.uri http://rightsstatements.org/vocab/InC/1.0/
dc.subject Fall 2018
dc.title Neuronal in vitro impact of Amblyommaamericanumsalivary glands extracts
dc.type Text
dc.date.published 2018
dc.citation.ctitle 3rd Entomology Undergraduate Research Poster Symposium. Manhattan, KS: Kansas State University, Department of Entomology.
dc.description.conference 3rd Entomology Undergraduate Research Poster Symposium. Manhattan, KS: Kansas State University, Department of Entomology.


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This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). Except where otherwise noted, the use of this item is bound by the following: This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).

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