A novel SPECT camera for molecular imaging of the prostate

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dc.contributor.author Cebula, Alan
dc.contributor.author Gilland, David
dc.contributor.author Su, Li-Ming
dc.contributor.author Wagenaar, Douglas
dc.contributor.author Bahadori, Amir A.
dc.date.accessioned 2016-10-20T17:08:45Z
dc.date.available 2016-10-20T17:08:45Z
dc.date.issued 2011-09-15
dc.identifier.uri http://hdl.handle.net/2097/34456
dc.description Citation: Proc. SPIE 8143, Medical Applications of Radiation Detectors, 814305 (September 14, 2011); doi:10.1117/12.896235
dc.description.abstract The objective of this work is to develop an improved SPECT camera for dedicated prostate imaging. Complementing the recent advancements in agents for molecular prostate imaging, this device has the potential to assist in distinguishing benign from aggressive cancers, to improve site-specific localization of cancer, to improve accuracy of needle-guided prostate biopsy of cancer sites, and to aid in focal therapy procedures such as cryotherapy and radiation. Theoretical calculations show that the spatial resolution/detection sensitivity of the proposed SPECT camera can rival or exceed 3D PET and further signal-to-noise advantage is attained with the better energy resolution of the CZT modules. Based on photon transport simulation studies, the system has a reconstructed spatial resolution of 4.8 mm with a sensitivity of 0.0001. Reconstruction of a simulated prostate distribution demonstrates the focal imaging capability of the system. en_US
dc.language.iso en_US en_US
dc.publisher SPIE en_US
dc.relation.uri https://doi.org/10.1117/12.896235 en_US
dc.rights This Item is protected by copyright and/or related rights. You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s). en_US
dc.rights.uri https://rightsstatements.org/page/InC/1.0/?language=en
dc.subject Single Photon Emission Computed Tomography (SPECT) en_US
dc.subject Prostate Imaging, Cadmium Zinc Telluride (CZT) en_US
dc.title A novel SPECT camera for molecular imaging of the prostate en_US
dc.type Article (publisher version) en_US
dc.date.published 2011 en_US
dc.citation.ctitle SPIE Proceedings en_US
dc.citation.doi 10.1117/12.896235 en_US
dc.citation.volume 8143 en_US
dc.description.conference Medical Applications of Radiation Detectors. San Diego, CA. 2011 en_US
dc.contributor.authoreid bahadori en_US


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