Guardian of Genetic Messenger-RNA-Binding Proteins

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dc.contributor.author Anji, Antje
dc.contributor.author Kumari, Meena
dc.date.accessioned 2016-09-20T17:37:29Z
dc.date.available 2016-09-20T17:37:29Z
dc.date.issued 2016-01-06
dc.identifier.uri http://hdl.handle.net/2097/34086
dc.description Citation: Anji, A., & Kumari, M. (2016). Guardian of Genetic Messenger-RNA-Binding Proteins. Biomolecules, 6(1), 18. doi:10.3390/biom6010004
dc.description.abstract RNA in cells is always associated with RNA-binding proteins that regulate all aspects of RNA metabolism including RNA splicing, export from the nucleus, RNA localization, mRNA turn-over as well as translation. Given their diverse functions, cells express a variety of RNA-binding proteins, which play important roles in the pathologies of a number of diseases. In this review we focus on the effect of alcohol on different RNA-binding proteins and their possible contribution to alcohol-related disorders, and discuss the role of these proteins in the development of neurological diseases and cancer. We further discuss the conventional methods and newer techniques that are employed to identify RNA-binding proteins.
dc.relation.uri https://doi.org/10.3390/biom6010004
dc.rights Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subject Alcohol
dc.subject Gene Expression
dc.subject Rna-Binding Proteins
dc.subject Mrna Splicing
dc.subject Neurological Diseases
dc.subject Cancer
dc.title Guardian of Genetic Messenger-RNA-Binding Proteins
dc.type Article
dc.date.published 2016
dc.citation.doi 10.3390/biom6010004
dc.citation.issn 2218-273X
dc.citation.issue 1
dc.citation.jtitle Biomolecules
dc.citation.spage 18
dc.citation.volume 6
dc.contributor.authoreid aanji
dc.contributor.authoreid mkumari


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