Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle

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dc.contributor.author Dickey, A. M.
dc.contributor.author Loy, J. D.
dc.contributor.author Bono, J. L.
dc.contributor.author Smith, T. P. L.
dc.contributor.author Apley, Michael D.
dc.contributor.author Lubbers, Brian V.
dc.contributor.author DeDonder, K. D.
dc.contributor.author Capik, S. F.
dc.contributor.author Larson, Robert L.
dc.contributor.author White, Bradley J.
dc.contributor.author Blom, J.
dc.contributor.author Chitko-McKown, C. G.
dc.contributor.author Clawson, M. L.
dc.date.accessioned 2016-09-20T17:28:01Z
dc.date.available 2016-09-20T17:28:01Z
dc.date.issued 2016-02-13
dc.identifier.uri http://hdl.handle.net/2097/33990
dc.description Citation: Dickey, A. M., Loy, J. D., Bono, J. L., Smith, T. P. L., Apley, M. D., Lubbers, B. V., . . . Clawson, M. L. (2016). Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle. Veterinary Research, 47, 11. doi:10.1186/s13567-016-0316-2
dc.description.abstract Moraxella bovoculi is a recently described bacterium that is associated with infectious bovine keratoconjunctivitis (IBK) or "pinkeye" in cattle. In this study, closed circularized genomes were generated for seven M. bovoculi isolates: three that originated from the eyes of clinical IBK bovine cases and four from the deep nasopharynx of asymptomatic cattle. Isolates that originated from the eyes of IBK cases profoundly differed from those that originated from the nasopharynx of asymptomatic cattle in genome structure, gene content and polymorphism diversity and consequently placed into two distinct phylogenetic groups. These results suggest that there are genetically distinct strains of M. bovoculi that may not associate with IBK.
dc.relation.uri https://doi.org/10.1186/s13567-016-0316-2
dc.rights Attribution 4.0 International (CC BY 4.0)
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Sp-Nov
dc.subject Strains
dc.subject Calves
dc.subject Vaccine
dc.subject Identification
dc.subject Phylogenies
dc.title Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle
dc.type Article
dc.date.published 2016
dc.citation.doi 10.1186/s13567-016-0316-2
dc.citation.issn 2151-0032
dc.citation.jtitle Veterinary Research
dc.citation.spage 11
dc.citation.volume 47
dc.contributor.authoreid mapley
dc.contributor.authoreid blubbers
dc.contributor.authoreid rlarson
dc.contributor.authoreid whiteb


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