Browsing College of Veterinary Medicine by Title

Now showing items 276-295 of 300

Structural and functional annotation of the porcine immunome

Dawson, Harry D.; Loveland, Jane E.; Pascal, Géraldine; Sang, Yongming; Blecha, Frank (2013-07-05)

Background: The domestic pig is known as an excellent model for human immunology and the two species share many pathogens. Susceptibility to infectious disease is one of the major constraints on swine performance, yet the ...
Study to evaluate the acaricidal efficacy of a single topical treatment with a topical combination of fipronil/amitraz/(S)-methoprene against Dermacentor variabilis on dogs

Dryden, Michael W.; Smith, Victorene E.; Kunkle, Bruce; Carithers, Doug (2012-12-07)

The objective of the study was to confirm the acaricidal efficacy of a single topical treatment of the combination of fipronil/amitraz/(S)-methoprene (CERTIFECT®) against induced infestations of Dermacentor variabilis. ...
Subdiffusion in Membrane Permeation of Small Molecules

Chipot, Christophe; Comer, Jeffrey R.

Within the solubility–diffusion model of passive membrane permeation of small molecules, translocation of the permeant across the biological membrane is traditionally assumed to obey the Smoluchowski diffusion equation, ...
Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses

Balzli, C.; Lager, K.; Vincent, A.; Gauger, P.; Brockmeier, S.; Miller, L.; Richt, Juergen A.; Ma, Wenjun; Suarez, D.; Swayne, D. E.

Background: The ability of pigs to become infected with low pathogenic avian influenza (LPAI) viruses and then generate mammalian adaptable influenza A viruses is difficult to determine. Yet, it is an important link to ...
Targeted Amplicon Sequencing for Single-Nucleotide-Polymorphism Genotyping of Attaching and Effacing Escherichia coli O26:H11 Cattle Strains via a High-Throughput Library Preparation Technique

Ison, Sarah A.; Delannoy, Sabine; Bugarel, Marie; Nagaraja, Tiruvoor G.; Renter, David G.; Bakker, Henk C. den; Nightingale, Kendra K.; Fach, Patrick; Loneragan, Guy H. (2016-01-15)

Enterohemorrhagic Escherichia coli (EHEC) O26:H11, a serotype within Shiga toxin-producing E. coli (STEC) that causes severe human disease, has been considered to have evolved from attaching and effacing E. coli (AEEC) ...
Temporal changes in the bacterial community of animal feces and their correlation with stable fly oviposition, larval development, and adult fitness

Albuquerque, Thais Aguiar De; Zurek, Ludek (2015-05-13)

Stable flies are blood-feeding insects with a great negative impact on animals world wide. Larvae develop primarily in animal manure and bacteria are essential for larval development; however, the principle of this dependence ...
Testosterone upregulates anion secretion across porcine vas deferens epithelia in vitro

Pierucci-Alves, Fernando; Duncan, Cameron L.; Schultz, Bruce D. (2013-06-27)

Testosterone induces and maintains prostaglandin-endoperoxide synthase 2 (PTGS2, also known as cyclooxygenase 2) expression in vas deferens epithelial cells, but it remains unknown whether this has a physiological role in ...
The Convergence of High-Consequence Livestock and Human Pathogen Research and Development: A Paradox of Zoonotic Disease

Michelotti, Julia M.; Yeh, Kenneth B.; Beckham, Tammy R.; Colby, Michelle M.; Dasgupta, Debanjana; Zuelke, Kurt A.; Olinger, Gene G. (2018-05-30)

The World Health Organization (WHO) estimates that zoonotic diseases transmitted from animals to humans account for 75 percent of new and emerging infectious diseases. Globally, high-consequence pathogens that impact ...
The impact of item-writing flaws and item complexity on examination item difficulty and discrimination value

Rush, Bonnie R.; Rankin, David C.; White, Bradley J.

Background: Failure to adhere to standard item-writing guidelines may render examination questions easier or more difficult than intended. Item complexity describes the cognitive skill level required to obtain a correct ...
Toll-like receptor (TLR) 2 and TLR4 gene expression in canine heart

Linde, Annika; Blecha, Frank; Melgarejo, Tonatiuh (2013-05-29)

Toll-like receptors (TLRs) are archetypal pattern recognition receptors of immediate importance for an efficacious innate immune response. TLRs exhibit marked differential tissue activity and their levels within a discrete ...
Toll-like receptor 3 activation decreases porcine arterivirus infection

Sang, Yongming; Ross, Christopher R.; Rowland, Raymond R. R.; Blecha, Frank (2013-05-29)

Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that initiates infection in pulmonary alveolar macrophages (PAMs), elicits weak immune responses, and establishes a persistent infection. To ...
Transcription of Ehrlichia chaffeensis genes is accomplished by RNA polymerase holoenzyme containing either sigma 32 or sigma 70

Liu, Huitao; Ohlen, Tonia Von; Cheng, Chuanmin; Faburay, Bonto; Ganta, Roman R. (2013-11-21)

Bacterial gene transcription is initiated by RNA polymerase containing a sigma factor. To understand gene regulation in Ehrlichia chaffeensis, an important tick-transmitted rickettsiae responsible for human monocytic ...
Transmission of scrapie prions to primate after an extended silent incubation period

Comoy, E. E.; Mikol, J.; Luccantoni-Freire, S.; Correia, E.; Lescoutra-Etchegaray, N.; Durand, V.; Dehen, C.; Andreoletti, O.; Casalone, C.; Richt, Juergen A.; Greenlee, J. J.; Baron, T.; Benestad, S. L.; Brown, P.; Deslys, J. P.
The Tribolium castaneum cell line TcA: a new tool kit for cell biology

Silver, Kristopher S.; Jiang, Hongbo; Fu, Jinping; Phillips, Thomas W.; Beeman, Richard W.; Park, Yoonseong (2015-04-08)

The red flour beetle, Tribolium castaneum, is an agriculturally important insect pest that has been widely used as a model organism. Recently, an adherent cell line (BCIRL-TcA-CLG1 or TcA) was developed from late pupae of ...
Two-Dimensional Fluorescence Difference Spectroscopy to Characterize Nanoparticles and their Interactions

Hurst, Miranda N.; DeLong, Robert K.

Two dimensional fluorescence difference spectroscopy (2D FDS) detects nanoparticle interactions following surface functionalization and biomolecule loading by generating a spectral signature of the fluorescent intensity ...
Unbalanced Activation of Glutathione Metabolic Pathways Suggests Potential Involvement in Plant Defense against the Gall Midge Mayetiola destructor in Wheat

Liu, Xuming M.; Zhang, S. Z.; Whitworth, R. J.; Stuart, J. J.; Chen, M. S.
Use of PCR to identify Leptospira in kidneys of big brown bats (Eptesicus fuscus) in Kansas and Nebraska, USA

Harkin, Kenneth R.; Hays, Michael P.; Davis, Rolan D.; Moore, Michael C. (2014-11-04)

Bats have been implicated as potential carriers of Leptospira as a result of surveys, mostly in Australia and South America. We measured the prevalence of pathogenic leptospires in kidneys of bats from Kansas and Nebraska. ...
Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4(+) T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host

McGill, Jodi L.; Nair, Arathy D.S.; Cheng, C. M.; Rusk, R. A.; Jaworski, Deborah C.; Ganta, Roman R.

Ehrlichia chaffeensis is a tick-borne rickettsial pathogen and the causative agent of human monocytic ehrlichiosis. Transmitted by the Amblyomma americanum tick, E. chaffeensis also causes disease in several other vertebrate ...
Validation of the rapid fluorescent focus inhibition test (RFFIT) for rabies virus neutralizing antibodies in clinical samples

Kostense, Stefan; Moore, Susan M.; Companjen, Arjen; Bakker, Alexander B. H.; Marissen, Wilfred E.; von Eyben, Rie; Weverling, Gerrit Jan; Hanlon, Cathleen A.; Goudsmit, Jaap (2012-08-17)

Monoclonal antibodies are successful biologics in treating a variety of diseases, including the prevention or treatment of viral infections. CL184 is a 1:1 combination of two human monoclonal IgG1 antibodies (CR57 and ...
Viruses of the family Bunyaviridae: are all available isolates reassortants?

Briese, Thomas; Calisher, Charles H.; Higgs, Stephen (2014-05-01)

Viruses of the family Bunyaviridae (the bunyaviruses) possess three distinct linear, single-stranded, negative sense or ambisense RNA segments (large, medium, and small). Dual infections of arthropod and perhaps vertebrate ...