Splenopancreatic ductal adenocarcinoma with multiorgan metastasis in a northern water snake (Nerodia sipedon)

K-REx Repository

Show simple item record

dc.contributor.author Matthews, Mary Ellen
dc.contributor.author Eshar, David N.
dc.contributor.author Delk, Katie W.
dc.contributor.author Pohlman, Lisa M.
dc.contributor.author Andrews, Gordon A.
dc.date.accessioned 2014-11-06T16:38:53Z
dc.date.available 2014-11-06T16:38:53Z
dc.date.issued 2014-11-06
dc.identifier.uri http://hdl.handle.net/2097/18646
dc.description.abstract A 16-yr-old northern water snake (Nerodia sipedon) presented with a large, firm midcoelomic swelling. A complete blood count, survey radiographs, coelomic ultrasound, and fine needle aspirate of the mass were performed. Survey radiographs revealed a soft tissue opacity mass. Ultrasonographic examination confirmed the presence of the mass but could not aid in its visceral localization. After 2 weeks, the snake presented again because of continued anorexia and poor quality of life. Euthanasia was performed. Gross necropsy revealed a multilobulated mass attached to and effacing the splenopancreas. Histologically, the mass was composed of cuboidal to columnar neoplastic epithelial cells forming tubules surrounded by variable amounts of fibrovascular stroma. Histological examination and immunohistochemical staining of other tissues revealed local invasion in the subserosa and tunica muscularis of the stomach, metastasis within the liver, in the mesovarium, and an intravascular metastasis within the ventricle of the heart surrounded by a thrombus. en_US
dc.language.iso en_US en_US
dc.relation.uri http://www.bioone.org/doi/full/10.1638/2013-0199R.1 en_US
dc.rights Permission to archive granted by American Association of Zoo Veterinarians, Sept. 25, 2014. en_US
dc.subject Ductal adenocarcinoma en_US
dc.subject Immunohistochemistry en_US
dc.subject Nerodia sipedon en_US
dc.subject Northern water snake en_US
dc.subject Splenopancreas en_US
dc.title Splenopancreatic ductal adenocarcinoma with multiorgan metastasis in a northern water snake (Nerodia sipedon) en_US
dc.type Article (publisher version) en_US
dc.date.published 2014 en_US
dc.citation.doi 10.1638/2013-0199R.1 en_US
dc.citation.epage 440 en_US
dc.citation.issue 2 en_US
dc.citation.jtitle Journal of Zoo and Wildlife Medicine en_US
dc.citation.spage 437 en_US
dc.citation.volume 45 en_US
dc.contributor.authoreid deshar en_US
dc.contributor.authoreid pohlman en_US
dc.contributor.authoreid gandrews en_US

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search K-REx

Advanced Search


My Account


Center for the

Advancement of Digital