Consumption of cross-linked resistant starch (RS4XL) on glucose and insulin responses in humans

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Show simple item record Al-Tamimi, Enas K. Seib, Paul A. Snyder, Brian S. Haub, Mark D. 2009-09-25T16:13:31Z 2009-09-25T16:13:31Z 2009-09-25T16:13:31Z
dc.description.abstract Objective: The objective was to compare the postprandial glycemic and insulinemic responses to nutrition bars containing either cross-linked RS type 4 (RS4XL) or standard wheat starch in normoglycemic adults (n=13; age= 27±5 yr; BMI=25±3 kg/m2). Methods: Volunteers completed three trials during which they consumed a glucose beverage (GLU), a puffed wheat control bar (PWB), and a bar containing cross-linked RS4 (RS4XL) matched for available carbohydrate content. Serial blood samples were collected over two hours and glucose and insulin concentrations were determined and the incremental area under the curve (iAUC) was calculated. Results: The RS4 XL peak glucose and insulin concentrations were lower than the GLU and PWB (p<0.05). The iAUC for glucose and insulin were lower following ingestion of RS4 compared with the GLU and PWB trials. Conclusions: These data illustrate, for the first time, that directly substituting standard starch with RS4XL, while matched for available carbohydrates, attenuated postprandial glucose and insulin levels in humans. It remains to be determined whether this response was due to the dietary fiber and/or resistant starch aspects of the RS4XL bar. en_US
dc.relation.uri en_US
dc.rights Copyright © 2010 Enas K. Al-Tamimi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. en_US
dc.subject Diabetes en_US
dc.subject Obesity en_US
dc.subject Insulin en_US
dc.subject Fiber en_US
dc.subject Prebiotic en_US
dc.subject Glycemic index en_US
dc.title Consumption of cross-linked resistant starch (RS4XL) on glucose and insulin responses in humans en_US
dc.type Article (publisher version) en_US 2009 en_US
dc.citation.doi 10.1155/2010/651063 en_US
dc.citation.epage 6 en_US
dc.citation.issue 651063 en_US
dc.citation.jtitle Journal of nutrition and metabolism en_US
dc.citation.spage 1 en_US
dc.citation.volume 2010 en_US
dc.contributor.authoreid haub en_US
dc.contributor.authoreid paseib
dc.contributor.authoreid bsnyder

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