Browsing Biology by Author "Gillaspie, Sarah"

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Browsing Biology by Author "Gillaspie, Sarah"

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  • Tang, Leiming; Morris, Jacob; Wan, Ji; Moore, Chelsea; Fujita, Yoshihiko; Gillaspie, Sarah; Aube, Eric; Nanda, Jagpreet; Marques, Maud; Jangal, Maika; Anderson, Abbey; Cox, Christian; Hiraishi, Hiroyuki; Dong, Leiming; Saito, Hirohide; Singh, Chingakham Ranjit; Witcher, Michael; Topisirovic, Ivan; Qian, Shu-Bing; Asano, Katsura (2017-11-16)
    In the human genome, translation initiation from nonAUG codons plays an important role in various gene regulation programs. However, mechanisms regulating the non-AUG initiation rate remain poorly understood. Here, we show ...
  • Kozel, Caitlin; Thompson, Brytteny; Hustak, Samantha; Moore, Chelsea; Nakashima, A.; Singh, Chingakham Ranjit; Reid, Megan; Cox, Christian; Papadopoulos, E.; Luna, R. E.; Anderson, Abbey; Tagami, H.; Hiraishi, Hiroyuki; Slone, Emily A.; Yoshino, K.; Asano, Masayo; Gillaspie, Sarah; Nietfeld, Jerome; Perchellet, Jean-Pierre; Rothenburg, Stefan; Masai, H.; Wagner, G.; Beeser, Alexander; Kikkawa, U.; Fleming, Sherry D.; Asano, Katsura
    ATF4 is a pro-oncogenic transcription factor whose translation is activated by eIF2 phosphorylation through delayed re-initiation involving two uORFs in the mRNA leader. However, in yeast, the effect of eIF2 phosphorylation ...

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