Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder

K-REx Repository

Show simple item record Cino Ozuna, Ada Giselle Rowland, Raymond R. R. Nietfeld, Jerome C. Kerrigan, Maureen A. Dekkers, Jack C. M. Wyatt, Carol R. 2013-04-02T16:50:50Z 2013-04-02T16:50:50Z 2012-08-16
dc.description.abstract Weaned pigs from a line bred for increased feed efficiency were enrolled in a study of the role of host genes in the response to infection with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). However, 4 of the pigs were euthanized early in the study due to weight loss with poor body condition and illness; 2 pigs, before PRRSV infection, and the other 2, approximately 2 weeks after virus inoculation. The 2 inoculated pigs failed to produce PRRSV-specific antibodies. Gross findings included pneumonia, absence of a detectable thymus, and small secondary lymphoid tissues. Histologically, lymph nodes, spleen, tonsils, and Peyer’s patches were sparsely cellular with decreased to absent T and B lymphocytes. en_US
dc.language.iso en_US en_US
dc.relation.uri en_US
dc.subject Clinical pathology en_US
dc.subject Immunohistochemistry en_US
dc.subject Lymphoid tissues en_US
dc.subject Pig diseases en_US
dc.subject Primary immunodeficiency en_US
dc.title Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder en_US
dc.type Article (author version) en_US 2013 en_US
dc.citation.doi 10.1177/0300985812457790 en_US
dc.citation.epage 146 en_US
dc.citation.issue 1 en_US
dc.citation.jtitle Veterinary Pathology en_US
dc.citation.spage 144 en_US
dc.citation.volume 50 en_US
dc.contributor.authoreid rrowland en_US
dc.contributor.authoreid jcnietfe en_US
dc.contributor.authoreid mkerriga en_US
dc.contributor.authoreid cwyatt en_US

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search K-REx

Advanced Search


My Account


Center for the

Advancement of Digital