Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder

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dc.contributor.author Cino Ozuna, Ada Giselle
dc.contributor.author Rowland, Raymond R. R.
dc.contributor.author Nietfeld, Jerome C.
dc.contributor.author Kerrigan, Maureen A.
dc.contributor.author Dekkers, Jack C. M.
dc.contributor.author Wyatt, Carol R.
dc.date.accessioned 2013-04-02T16:50:50Z
dc.date.available 2013-04-02T16:50:50Z
dc.date.issued 2013-04-02
dc.identifier.uri http://hdl.handle.net/2097/15441
dc.description.abstract Weaned pigs from a line bred for increased feed efficiency were enrolled in a study of the role of host genes in the response to infection with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). However, 4 of the pigs were euthanized early in the study due to weight loss with poor body condition and illness; 2 pigs, before PRRSV infection, and the other 2, approximately 2 weeks after virus inoculation. The 2 inoculated pigs failed to produce PRRSV-specific antibodies. Gross findings included pneumonia, absence of a detectable thymus, and small secondary lymphoid tissues. Histologically, lymph nodes, spleen, tonsils, and Peyer’s patches were sparsely cellular with decreased to absent T and B lymphocytes. en_US
dc.language.iso en_US en_US
dc.relation.uri http://vet.sagepub.com/content/50/1/144 en_US
dc.subject Clinical pathology en_US
dc.subject Immunohistochemistry en_US
dc.subject Lymphoid tissues en_US
dc.subject Pig diseases en_US
dc.subject Primary immunodeficiency en_US
dc.title Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder en_US
dc.type Article (author version) en_US
dc.date.published 2013 en_US
dc.citation.doi doi:10.1177/0300985812457790 en_US
dc.citation.epage 146 en_US
dc.citation.issue 1 en_US
dc.citation.jtitle Veterinary Pathology en_US
dc.citation.spage 144 en_US
dc.citation.volume 50 en_US
dc.contributor.authoreid rrowland en_US
dc.contributor.authoreid jcnietfe en_US
dc.contributor.authoreid mkerriga en_US
dc.contributor.authoreid cwyatt en_US


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