New 2-D graphical representation of DNA sequences

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dc.contributor.author Wang, Jiasong
dc.contributor.author Wang, Weiqun
dc.date.accessioned 2008-04-28T19:23:38Z
dc.date.available 2008-04-28T19:23:38Z
dc.date.issued 2008-04-28T19:23:38Z
dc.identifier.uri http://hdl.handle.net/2097/647
dc.description.abstract In this paper we present a novel 2-D graphical representation of DNA sequences in the first quadrant of Cartesian coordinate system. This representation has been mathematically proved to have a zero length of circuit, i.e. without degeneracy. Given any point considered in a DNA sequence, the number of A, T, G, and C from the starting point could be calculated based upon an iterative comparison method. Furthermore, we deduced the fractal dimension of our graphical representation, which can be used to classify DNA sequences. Using the advantage of our novel graphical representation, a new graphical representation of protein sequence has been suggested, which may represent codon by codon or amino acid by amino acid. To apply this new representation to the genetic codons, we found the property of double stochastic matrix for genetic code based matrix can be achieved as long as A=U and C=G in spite of any assigned positive numbers beside A=U=2 and C=G=3. en
dc.rights Electronic version of an article published as Biophysical Reviews and Letters (BRL) Vol: 1 Issue: 2 (April 2006) Page: 133 - 140] DOI: 10.1142/S1793048006000124 © [copyright World Scientific Publishing Company] http://worldscinet.lib.tsinghua.edu.cn/archive.nsp en
dc.subject 2-D graphical representation en
dc.subject DNA sequences en
dc.subject Degeneracy en
dc.subject Fractal dimension en
dc.subject Graphical representation of protein en
dc.subject Genetic code en
dc.subject Double stochastic matrices
dc.title New 2-D graphical representation of DNA sequences en
dc.type Article (author version) en
dc.date.published 2006 en
dc.citation.doi DOI: 10.1142/S1793048006000124 en
dc.citation.epage 140 en
dc.citation.issn 1793-0480 en
dc.citation.issue 2 en
dc.citation.jtitle Biophysical reviews and letters en
dc.citation.spage 133 en
dc.citation.volume 1 en
dc.contributor.authoreid wwang

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