Inflammatory response of feedlot cattle to clostridial vaccination: a comparison of 7-way bacterin-toxoid and C&D toxoid

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dc.contributor.author Stokka, G.L.
dc.contributor.author Brandt, Robert T., Jr.
dc.contributor.author Edwards, A.J.
dc.contributor.author Spire, M.F.
dc.contributor.author Smith, J.E.
dc.date.accessioned 2010-10-14T17:54:17Z
dc.date.available 2010-10-14T17:54:17Z
dc.date.issued 2010-10-14T17:54:17Z
dc.identifier.uri http://hdl.handle.net/2097/6318
dc.description.abstract Twenty-four finishing steers (758 lb) were subcutaneously vaccinated and revaccinated 31 days later with 1) sterile saline, 2) a clostridial perfringens C&D toxoid, or 3) a 7-way clostridial bacterin-toxoid to evaluate the effects of vaccine type on inflammatory response in feedlot cattle. Injection site reactions were most severe (P<.05) and persistent for 7-way bacterin-toxoid and were accompanied by elevated (P<.05) blood haptoglobin levels indicative of acute inflammation. Revaccination with 7-way bacterin-toxoid reduced (P<.05) feed consumption for a 4-day period postvaccination. Although some reactions were severe, they appeared transient because blood parameters and volume of injection site reactions returned to baseline levels 25 to 60 days after injection. Performance over the entire feeding period was not significantly altered by treatment. We strongly recommend that clostridial products be used subcutaneously only, to minimize potential damage to carcass tissue from intramuscular injection. en_US
dc.publisher Kansas State University. Agricultural Experiment Station and Cooperative Extension Service en_US
dc.relation.isPartOf Cattlemen’s Day, 1993 en_US
dc.relation.isPartOf Kansas Agricultural Experiment Station contribution; no. 93-318-S en_US
dc.relation.isPartOf Report of progress (Kansas State University. Agricultural Experiment Station and Cooperative Extension Service); 678 en_US
dc.subject Beef en_US
dc.subject Vaccination en_US
dc.subject Cattle en_US
dc.subject Injection site en_US
dc.title Inflammatory response of feedlot cattle to clostridial vaccination: a comparison of 7-way bacterin-toxoid and C&D toxoid en_US
dc.type Conference paper en_US
dc.date.published 1993 en_US
dc.citation.epage 144 en_US
dc.citation.spage 142 en_US
dc.description.conference Cattlemen's Day, 1993, Kansas State University, Manhattan, KS, March 5, 1993 en_US

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