Effects of flax supplementation and a Revalor-S implant on circulating insulin-like growth factor 1 (IGF-1) and muscle IGF-1 mRNA levels in finishing cattle

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dc.contributor.author Dunn, J.D.
dc.contributor.author Kayser, J.P.
dc.contributor.author Waylan, A.T.
dc.contributor.author Sissom, E.K.
dc.contributor.author Johnson, B.J.
dc.contributor.author Drouillard, James S.
dc.date.accessioned 2010-08-04T17:41:26Z
dc.date.available 2010-08-04T17:41:26Z
dc.date.issued 2010-08-04T17:41:26Z
dc.identifier.uri http://hdl.handle.net/2097/4478
dc.description.abstract Sixteen crossbred steers weighing 875 lb were used to evaluate the effects of a 5% ground flaxseed supplement and a combined trenbolone acetate/estradiol (TBA/E2) growth promoting implant, Revalor-S®, on both circulating insulin-like growth factor-1 (IGF-1) and local muscle IGF-1 mRNA concentrations. Steers were randomly assigned to one of four treatments: . 1) Flax/Implant, 2) No Flax/ Implant, 3) Flax/No Implant, 4) No Flax/No Implant. Serum was harvested from blood collected via jugular venipuncture on day 0 (before implantation or flax addition), 14, and 28. Muscle biopsy samples were obtained from the longissimus muscle on days 0, 14, and 28. Implanted steers had 52 and 84% higher (P<0.05) circulating IGF-1 levels than non-implanted steers on days 14 and 28, respectively. Cattle fed diets without flax had higher levels of muscle IGF-1 mRNA than cattle fed diets with flax on day 28 (4.4-fold, P<0.01). Our data support that the administration of a combined TBA/E2 growth promotant increases circulating IGF-1 and local muscle IGF-1 mRNA concentrations in finishing cattle. However, this increase in muscle IGF-1 mRNA appears to be attenuated by the addition of a dietary flax supplement. en_US
dc.publisher Kansas State University. Agricultural Experiment Station and Cooperative Extension Service en_US
dc.relation.isPartOf Cattlemen's Day, 2003 en_US
dc.relation.isPartOf Kansas Agricultural Experiment Station contribution; no. 03-272-S en_US
dc.relation.isPartOf Report of progress (Kansas State University. Agricultural Experiment Station and Cooperative Extension Service); 908 en_US
dc.subject Beef en_US
dc.subject Flax en_US
dc.subject Revalor-S implant en_US
dc.subject Growth factor 1 (IGF-1) en_US
dc.subject Muscle IGF-1 mRNA en_US
dc.subject Finishing cattle en_US
dc.title Effects of flax supplementation and a Revalor-S implant on circulating insulin-like growth factor 1 (IGF-1) and muscle IGF-1 mRNA levels in finishing cattle en_US
dc.type Conference paper en_US
dc.date.published 2003 en_US
dc.citation.epage 202 en_US
dc.citation.spage 199 en_US
dc.description.conference Cattlemen's Day, 2003, Kansas State University, Manhattan, KS, March 7, 2003 en_US
dc.contributor.authoreid jdrouill en_US

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