A new type of ceramic membrane reactor is proposed for the continuous enzymatic
synthesis of oligosaccharides using native enzyme. Beta-Galactosidase (EC
3.2.1.23) catalyses the hydrolysis of lactose to the monosaccharides glucose and
galactose and also the transgalactosylation reaction to produce galactosyloligosaccharides
(GOS). GOS are non-digestible oligosaccharides which are
recognized as prebiotics. GOS consist of a number of oligosaccharides with varying
ß-glycosidic linkages depending on the enzyme source. In this work, the results for
the continuous production of GOS from lactose by means of physically-confined ß-
Galactosidase in a novel ceramic membrane reactor system are presented.