Hydrocortisone acetate-injected piglets have a larger pancreas and greater mucosal weight and lactase, maltase, and sucrose activities in the duodenum

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dc.contributor.author Kreikemeier, K.K.
dc.contributor.author Harmon, D.L.
dc.contributor.author Nelssen, Jim L.
dc.date.accessioned 2010-04-15T21:48:47Z
dc.date.available 2010-04-15T21:48:47Z
dc.date.issued 2010-04-15T21:48:47Z
dc.identifier.uri http://hdl.handle.net/2097/3639
dc.description.abstract One litter of 12 piglets was used in a completely random design to evaluate the effects of hydrocortisone acetate injections on organ weight and carbohydrase activities. Dams' milk was the only food source available to the piglets. When they were 7 d old, six pigs were injected with hydrocortisone acetate (50 mg/kg BW; 50 mg/ml) and six others were injected with an equal volume of saline (1 ml/kg BW). When the pigs were 14 d old, tissues were collected, weighed, and analyzed for carbohydrase activities. Hydrocortisone acetate injection had no effect on pig daily gain (d 7 to 14), liver weight, spleen weight, or small intestinal (SI) length. However, it did increase pancreatic weight by 29%. Consequently, total pancreatic alpha-amylase was 38% greater in hydrocortisone-injected pigs. Hydrocortisone also increased duodenal mucosal weight (per cm of SI) by 23%, duodenal lactase activity (per cm of SI) by 44%, duodenal maltase activity (per cm of SI) by 163% and duodenal sucrase activity (per cm of SI) by 214%. There was little effect on disaccharidase activities in the jejunum or ileum. We conclude that hydrocortisone acetate may be useful to stimulate pancreatic growth and duodenal mucosal weight as well as lactase, maltase, and sucrase activity in 7-d-old pigs. en_US
dc.publisher Kansas State University. Agricultural Experiment Station and Cooperative Extension Service en_US
dc.relation.isPartOf Swine day, 1989 en_US
dc.relation.isPartOf Kansas Agricultural Experiment Station contribution; no. 90-163-S en_US
dc.relation.isPartOf Report of progress (Kansas State University. Agricultural Experiment Station and Cooperative Extension Service); 581 en_US
dc.subject Swine en_US
dc.subject Piglet en_US
dc.subject Glucocorticoid en_US
dc.subject Pancreas en_US
dc.subject Small intestine en_US
dc.subject Intestinal mucosa en_US
dc.subject Carbohydrases en_US
dc.title Hydrocortisone acetate-injected piglets have a larger pancreas and greater mucosal weight and lactase, maltase, and sucrose activities in the duodenum en_US
dc.type Conference paper en_US
dc.date.published 1989 en_US
dc.citation.epage 98 en_US
dc.citation.spage 93 en_US
dc.description.conference Swine Day, Manhattan, KS, November 16, 1989 en_US
dc.contributor.authoreid jnelssen en_US

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