Experimental and Modeling Study of Galactosyl-Oligosaccharides Formation in Continuous Recycle Membrane Reactors (CRMR)

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dc.contributor.author Gonzalez, Roberto
dc.contributor.author Ebrahimi, Mehrdad
dc.contributor.author Czermak, Peter
dc.date.accessioned 2010-04-05T21:01:32Z
dc.date.available 2010-04-05T21:01:32Z
dc.date.issued 2010-04-05T21:01:32Z
dc.identifier.uri http://hdl.handle.net/2097/3507
dc.description.abstract Galactosyl-oligosaccharides (GOS) can be produced with native enzymes in Continuous Recycle Membrane Reactors (CRMR) or with immobilized enzymes in Plug Flow Bed Reactors (PFBR). In this paper a simple three kinetic constants model was implemented and used to define the optimal operation conditions to obtain a higher GOS yield. Experimental GOS yield and productivity obtained with CRMR were in good agreement with simulated results. The advantages of using single CRMR, two coupled CRMR and single CRMR coupled with Simulated Moving Bed Chromatography (SMBC), for product separation and continuous lactose recycling, were investigated with a modeling and experimental study. Experimental studies for single CRMR showed a 89 % higher amount of produced GOS than reports from immobilized enzymes in Plug Flow Bed Reactors (PFBR). Two coupled CRMR produced a 25 % higher amount of GOS than single CRMR. Simulated results with CRMR and SMBC for continuous lactose recycling showed 45% higher GOS amount than single CRMR. The results prove the feasibility and advantages of GOS production in single or series CRMR with native enzymes with or without lactose recycling. en_US
dc.relation.uri http://www.bentham.org/open/tofsj/ en_US
dc.subject Oligosaccharides en_US
dc.subject Lactose en_US
dc.subject Enzymatic catalysis en_US
dc.subject Continuous recycle membrane reactors en_US
dc.subject Ultra filtration en_US
dc.subject Plug flow bed reactor en_US
dc.title Experimental and Modeling Study of Galactosyl-Oligosaccharides Formation in Continuous Recycle Membrane Reactors (CRMR) en_US
dc.type Article (publisher version) en_US
dc.date.published 2009 en_US
dc.citation.doi 10.2174/1874256400903010001 en_US
dc.citation.epage 9 en_US
dc.citation.jtitle The Open Food Science Journal en_US
dc.citation.spage 1 en_US
dc.citation.volume 3 en_US
dc.contributor.authoreid pczermak en_US

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