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Please use this identifier to cite or link to this item: http://hdl.handle.net/2097/1724

Title: Consumption of cross-linked resistant starch (RS4XL) on glucose and insulin responses in humans
Authors: Al-Tamimi, Enas K.
Seib, Paul A.
Snyder, Brian S.
Haub, Mark D.
Publication Date: 2009
Type: Article (publisher version)
Journal: Journal of nutrition and metabolism
Volume: 2010
Issue: 651063
Starting Page: 1
Ending Page: 6
Permissions: Copyright © 2010 Enas K. Al-Tamimi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Diabetes
Obesity
Insulin
Fiber
Prebiotic
Glycemic index
Abstract: Objective: The objective was to compare the postprandial glycemic and insulinemic responses to nutrition bars containing either cross-linked RS type 4 (RS4XL) or standard wheat starch in normoglycemic adults (n=13; age= 27±5 yr; BMI=25±3 kg/m2). Methods: Volunteers completed three trials during which they consumed a glucose beverage (GLU), a puffed wheat control bar (PWB), and a bar containing cross-linked RS4 (RS4XL) matched for available carbohydrate content. Serial blood samples were collected over two hours and glucose and insulin concentrations were determined and the incremental area under the curve (iAUC) was calculated. Results: The RS4 XL peak glucose and insulin concentrations were lower than the GLU and PWB (p<0.05). The iAUC for glucose and insulin were lower following ingestion of RS4 compared with the GLU and PWB trials. Conclusions: These data illustrate, for the first time, that directly substituting standard starch with RS4XL, while matched for available carbohydrates, attenuated postprandial glucose and insulin levels in humans. It remains to be determined whether this response was due to the dietary fiber and/or resistant starch aspects of the RS4XL bar.
URI: http://hdl.handle.net/2097/1724
Appears in Collections:Human Nutrition

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