Browsing Anatomy and Physiology by Subject "Angiotensin II type 2 receptor"

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Intratracheal administration of a nanoparticle-based therapy with the angiotensin II type 2 receptor gene attenuates lung cancer growth

Kawabata, Atsushi; Baoum, Abdulgader; Ohta, Naomi; Jacquez, Stephanie; Seo, Gwi-Moon; Berkland, Cory; Tamura, Masaaki (2012-11-06)

Targeted gene delivery, transfection efficiency and toxicity concerns remain a challenge for effective gene therapy. In this study, we dimerized the HIV-1 TAT peptide and formulated a nanoparticle vector (dTAT NP) to ...