Diagnostic performance of P wave duration in the identification of left atrial enlargement in dogs

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dc.contributor.author Savarino, P.
dc.contributor.author Borgarelli, Michele
dc.contributor.author Tarducci, A.
dc.contributor.author Crosara, S.
dc.contributor.author Bello, Nora M.
dc.contributor.author Mariocco, M. L.
dc.date.accessioned 2012-06-27T18:52:17Z
dc.date.available 2012-06-27T18:52:17Z
dc.date.issued 2012-06-27
dc.identifier.uri http://hdl.handle.net/2097/13962
dc.description.abstract Objectives: To determine sensitivity and specificity of P wave duration in the identification of left atrial enlargement (LAE) in dogs. Methods: Electrocardiograms (ECG) from normal dogs and dogs with various cardiovascular diseases were evaluated. Inclusion criteria were the availability of an ECG showing a stable isoelectric line, easily recognizable P waves and good quality 2D echocardiographic estimate of left atrial dimensions using the left atrial to aortic root ratio (LA/Ao). Using a metal caliper system, P wave duration was measured to the nearest 10 msec for six consecutive heart beats; data were then averaged for each dog. The accuracy of P wave duration in predicting LAE was determined using a Receiver Operating Characteristic (ROC) analysis. Results: 156 dogs were included in the study. Average P wave durations of 20, 30, 40 and 50 msec yielded sensitivities of 100%, 85%, 68% and 40% and specificities of 0%, 16.04%, 64.15% and 93.4%, respectively, for the diagnosis of LAE by echocardiography. The estimated Area Under Curve (AUC) of the ROC curve was 0.70 (95% confidence interval: 0.60-0.80). Clinical significance: The diagnostic performance of P wave duration for identification of LAE in dogs presents considerable limitations. en_US
dc.relation.uri http://onlinelibrary.wiley.com/doi/10.1111/jsap.2012.53.issue-5/issuetoc en_US
dc.rights With acknowledgement to the British Small Animal Veterinary Association and Blackwell Publishing. The definitive version is available at http://onlinelibrary.wiley.com/. en_US
dc.subject P wave en_US
dc.subject Dog en_US
dc.subject Left atrial enlargement en_US
dc.title Diagnostic performance of P wave duration in the identification of left atrial enlargement in dogs en_US
dc.type Article (author version) en_US
dc.date.published 2012 en_US
dc.citation.doi doi:10.1111/j.1748-5827.2012.01200.x en_US
dc.citation.epage 272 en_US
dc.citation.issue 5 en_US
dc.citation.jtitle Journal of Small Animal Practice en_US
dc.citation.spage 267 en_US
dc.citation.volume 53 en_US
dc.contributor.authoreid mborgare en_US
dc.contributor.authoreid nbello en_US

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