Browsing Biochemistry and Molecular Biophysics Faculty Research and Publications by Subject "Growth-Factor Receptor"

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Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer

Duhachek-Muggy, Sara; Qi, Yue; Wise, Randi; Alyahya, Linda; Li, Hui; Hodge, Jacob; Zolkiewska, Anna

Background: ADAM12 is upregulated in human breast cancers and is a predictor of chemoresistance in estrogen receptor-negative tumors. ADAM12 is induced during epithelial-to-mesenchymal transition, a feature associated with ...