Browsing Chemistry by Title

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Browsing Chemistry by Title

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  • Li, Yifen; Syed, Lateef; Liu, Jianwei; Hua, Duy H.; Li, Jun (2012)
    We demonstrate the feasibility of a label-free electrochemical method to detect the kinetics of phosphorylation and dephosphorylation of surface-attached peptides catalyzed by kinase and phosphatase, respectively. The ...
  • Ploetz, Elizabeth A.; Smith, Paul E. (2011)
    An extension of the traditional Kirkwood-Buff (KB) theory of solutions is outlined which provides additional fluctuating quantities that can be used to characterize and probe the behavior of solution mixtures. Particle-energy ...
  • Alshetaiwi, Hamad S.; Balivada, Sivasai; Shrestha, Tej B.; Pyle, Marla M.; Basel, Matthew T.; Bossmann, Stefan H.; Troyer, Deryl L. (2013)
    Polymorphonuclear neutrophils (PMNs) are the most abundant circulating blood leukocytes. They are part of the innate immune system and provide a first line of defense by migrating toward areas of inflammation in response ...
  • Mandadapu, Sivakoteswara Rao; Weerawarna, Pathum M.; Prior, Allan M.; Uy, Roxanne Adeline Z.; Aravapalli, Sridhar; Alliston, Kevin R.; Lushington, Gerald H.; Kim, Yunjeong; Hua, Duy H.; Chang, Kyeong-Ok; Groutas, William C. (2013)
    The design, synthesis, and in vitro evaluation of the first macrocyclic inhibitor of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus are reported. The in vitro inhibitory activity (50% effective ...
  • Wang, Hongwang; Shrestha, Tej B.; Basel, Matthew T.; Dani, Raj K.; Seo, Gwi-Moon; Balivada, Sivasai; Pyle, Marla M.; Prock, Heidy; Koper, Olga B.; Thapa, Prem S.; Moore, David; Li, Ping; Chikan, Viktor; Troyer, Deryl L.; Bossmann, Stefan H. (2012)
    The targeted delivery of therapeutics to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage. Herein, we report the synthesis of a nanoplatform, which is composed ...
  • Perera, Ayomi S.; Wang, Hongwang; Shrestha, Tej B.; Troyer, Deryl L.; Bossmann, Stefan H. (2013)
    The mycobacterial porin MspA is one of the most stable channel proteins known to date. MspA forms vesicles at low concentrations in aqueous buffers. Evidence from dynamic light scattering, transmission electron microscopy ...
  • Kim, Yunjeong; George, David; Prior, Allan M.; Prasain, Keshar; Hao, Shuanghong; Le, Duy D.; Hua, Duy H.; Chang, Kyeong-Ok (2012)
    Recently our group has demonstrated that cellular triglycerides (TG) levels play an important role in rotavirus replication. In this study, we further examined the roles of the key enzymes for TG synthesis (lipogenesis) ...
  • Kang, Myungshim; Smith, Paul E. (2010)
    A pairwise preferential interaction model (PPIM), based on Kirkwood-Buff integrals, is developed to quantify and characterize the interactions between some of the functional groups commonly observed in peptides. The existing ...
  • Smith, Paul E. (2007)
    Recent results concerning the formulation and evaluation of preferential interactions in biological systems in terms of Kirkwood–Buff (KB) integrals are presented. In particular, experimental and simulated preferential ...
  • Aakeröy, Christer B.; Rajbanshi, Arbin; Metrangolo, Pierangelo; Resnati, Giuseppe; Parisi, Melchiorre F.; Desper, John; Pilati, Tullio (2012)
    A halogen-bonded capsule is obtained via directed assembly of a rigid tetra(3-pyridyl) cavitand and a flexible tetra(4-iodotetrafluorophenyl) calix[4]arene. The pyridyl nitrogen atoms from one cavitand molecule interact ...
  • Pierce, Veronica; Kang, Myungshim; Aburi, Mahalaxmi; Weerasinghe, Samantha; Smith, Paul E. (2008)
    The effect of cosolvents on biomolecular equilibria has traditionally been rationalized using simple binding models. More recently, a renewed interest in the use of Kirkwood–Buff (KB) theory to analyze solution mixtures ...
  • Prasain, Keshar; Nguyen, Thi D.T.; Gorman, Maureen J.; Barrigan, Lydia M.; Peng, Zeyu; Kanost, Michael R.; Syed, Lateef U.; Li, Jun; Zhu, Kun Yan; Hua, Duy H. (2012)
    Laccases are copper-containing oxidases that are involved in sclerotization of the cuticle of mosquitoes and other insects. Oxidation of exogenous compounds by insect laccases may have the potential to produce reactive ...
  • Abul-Haj, Mohammad; Aakeröy, Christer B.; Desper, John (2013)
    A series of silver(I) coordination compounds with the ligand 2-(4-pyridyl)imidazole 4-PyIm has been synthesized and crystallographically characterized in order to explore the role of counter ion, solvent and ligand charge ...
  • Chen, Feng; Smith, Paul E. (2007)
    Initial simulated values of the surface tension for the SPC/E water model have indicated excellent agreement with experiment. More recently, differing values have been obtained which are significantly lower than previous ...
  • Jose, Deepa; Matthiesen, John E.; Parsons, Christopher; Sorensen, Christopher M.; Klabunde, Kenneth J. (2012)
    Ligand capped metal entities come in two sizes; (1) molecular clusters of 10 – 200 metal atoms, and (2) nanoparticles of 2000 – 10000 metal atoms. In numerous cases, certain “magic sizes” have been found to be most accessible ...
  • Aakeröy, Christer B.; Sinha, Abhijeet S.; Epa, Kanishka N.; Chopade, Prashant D.; Smith, Michelle M.; Desper, John (2013)
    Oximes (RR'C=N-OH) represent an important class of organic compounds with a wide range of practical applications, but a systematic examination of the structural chemistry of such compounds has so far not been carried out. ...
  • Aakeröy, Christer B.; Chopade, Prashant D.; Quinn, Colette F.; Desper, John (2014)
    A set of COOH···N(pyridine) 5 hydrogen bonds have been utilized in the targeted synthesis of a cavitand-based assembly. A cavitand appended with four pyridyl groups was synthesized from a Suzuki coupling of a tetrabromocavitand ...
  • Pokhrel, Laxman; Kim, Yunjeong; Nguyen, Thi D.T.; Prior, Allan M.; Lu, Jianyu; Chang, Kyeong-Ok; Hua, Duy H. (2012)
    During the last decade, noroviruses have gained media attention as the cause of large scale outbreaks of gastroenteritis on cruise ships, dormitories, nursing homes, etc. Although noroviruses do not multiply in food or ...
  • Thapa, Mahendra; Kim, Yunjeong; Desper, John; Chang, Kyeong-Ok; Hua, Duy H. (2012)
    Influenza viruses are important pathogens that cause respiratory infections in humans and animals. In addition to vaccination, antiviral drugs against influenza virus play a significant role in controlling viral infections ...