Chemistry

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Chemistry

 

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  • Prior, Allan M.; Kim, Yunjeong; Weerasekara, Sahani; Moroze, Meghan; Alliston, Kevin R.; Uy, Roxanne Adeline Z.; Groutas, William C.; Chang, Kyeong-Ok; Hua, Duy H. (2013)
    A class of tripeptidyl transition state inhibitors containing a P1 glutamine surrogate, a P2 leucine, and a P3 arylalanines, was found to potently inhibit Norwalk virus replication in enzyme and cell based assays. An array ...
  • Alshetaiwi, Hamad S.; Balivada, Sivasai; Shrestha, Tej B.; Pyle, Marla M.; Basel, Matthew T.; Bossmann, Stefan H.; Troyer, Deryl L. (2013)
    Polymorphonuclear neutrophils (PMNs) are the most abundant circulating blood leukocytes. They are part of the innate immune system and provide a first line of defense by migrating toward areas of inflammation in response ...
  • Aakeröy, Christer B.; Wijethunga, Tharanga K.; Desper, John (2014)
    Bifurcated halogen bonds constructed from N-oxides and complementary halogen-bond donors provide the basis for a synthetic strategy for the deliberate assembly of molecular polygons in the solid state. The donor- and ...
  • Ding, Ying; Prasain, Keshar; Nguyen, Thi D. T.; Hua, Duy H.; Nguyen, Thu A. (2012)
    Gap junctions are intercellular channels connecting adjacent cells, allowing cells to transport small molecules. The loss of gap junctional intercellular communication (GJIC) is one of the important hallmarks of cancer. ...
  • Aakeröy, Christer B.; Epa, Kanishka N.; Forbes, Safiyyah; Desper, John (2013)
    Based on a systematic structural study of co-crystals of a ditopic probe molecule, (Z)-N,4-dihydroxybenzimidoyl cyanide, decorated with an –OH group and a cyanooxime moiety, it has been shown that in a competitive molecular ...