Development and use of recombinant gonadotropin-releasing hormone vaccines to sterilize cattle: a review

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dc.contributor.author Greer, J.
dc.contributor.author Rozell, Timothy G.
dc.date.accessioned 2011-07-22T13:51:05Z
dc.date.available 2011-07-22T13:51:05Z
dc.date.issued 2011-07-22
dc.identifier.uri http://hdl.handle.net/2097/10728
dc.description.abstract A possible alternative to conventional castration methods is the use of vaccines that can be injected in order to sterilize animals. One promising approach involves the use of a vaccine that causes cattle to produce an immune response against one of their own reproductive hormones, gonadotropin releasing hormone (GnRH). Immunization against GnRH results in a decrease in the amount of GnRH circulating within the animal's blood. Therefore, follicle stimulating hormone (FSH) and luteinizing hormone (LH) are not stimulated to be released, and, subsequently their levels required for reproductive function. Experimentation has shown that immunization against GnRH can effectively block reproductive function in an age-independent manner but has little effect on carcass and growth parameters. However, about 10% of cattle tested do not respond when immunized against GnRH, regardless of dosing regimen. Further research is needed to improve the efficiency of potential GnRH immunocastration vaccines. en_US
dc.publisher Kansas Agricultural Experiment Station and Cooperative Extension Service en_US
dc.relation.isPartOf Dairy Day, 1997 en_US
dc.relation.isPartOf Kansas Agricultural Experiment Station contribution; no. 98-100-S en_US
dc.relation.isPartOf Report of progress (Kansas Agricultural Experiment Station and Cooperative Extension Service); 792 en_US
dc.subject Gonadotropin releasing hormone en_US
dc.subject Follicle stimulating hormone en_US
dc.subject Luteinizing hormone en_US
dc.subject Antibody en_US
dc.subject Immunization en_US
dc.title Development and use of recombinant gonadotropin-releasing hormone vaccines to sterilize cattle: a review en_US
dc.type Conference paper en_US
dc.date.published 1997 en_US
dc.citation.epage 34 en_US
dc.citation.spage 32 en_US
dc.contributor.authoreid trozell en_US

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